Serving to formulators develop modern remedies for a number of pores and skin situations whereas addressing evolving regulatory compliance necessities, additional demonstrating DuPont’s dedication to good well being and wellness
WILMINGTON, Del., April 13, 2023 /PRNewswire/ — DuPont (NYSE: DD) right this moment introduced the launch of latest low-cyclosiloxane silicone elastomer blends and silicone resin blends in response to rising shopper demand for merchandise that tackle quite a lot of pores and skin issues. These new topical excipients additionally tackle the market’s want to satisfy evolving REACH compliance necessities and help DuPont’s and its clients’ shared dedication to the United Nations Sustainable Growth Targets (UN SDGs), particularly UNSDG No. 3 Good Well being and Wellness. Being requires defending individuals’s well being and well-being for all individuals of all ages.
“Over-the-counter and pharmaceutical merchandise for the remedy of scars, actinic keratosis, atopic dermatitis, psoriasis, and different pores and skin situations are rising to satisfy customers’ need to really feel good in any respect ages with out compromising pores and skin safety and drug efficacy,” stated DuPont. Reside Healthcare Options EMEA Regional Advertising and marketing Director Michele Vigliotti. “In the meantime, laws on shopper healthcare merchandise proceed to evolve to make sure security and decrease public danger.”
In response, DuPont Reside has developed 4 new low-cyclosiloxane silicone topical adjuvant blends. These merchandise are designed to assist clients obtain the brink for Substances of Very Excessive Concern (SVHC) proposed by REACH Regulation (EC) No. 1907/2006 for these cyclosiloxanes under 0.1%.
The brand new DuPont Reside silicone elastomer compounds are:
Reside TE-9320 silicone elastomer compound A mix of silicone elastomer community swollen in a unstable Dimethicone service (reference INCI names Dimethicone and Dimethicone Crosspolymer) is a non-occlusive rheology modifying agent with a pores and skin really feel characterised by smoothness and a lightweight, silky, non-greasy really feel. It accommodates lower than 0.1% D4, D5 and D6.
Reside TE-9330 silicone elastomer compound a mix of silicone elastomer community swollen in a non-volatile Dimethicone service (reference INCI names Dimethicone and Dimethicone Crosspolymer) is a non-occlusive thickener for anhydrous and water-in-oil emulsions. It offers a easy, silky really feel and accommodates lower than 0.1% D4, D5 and D6.
Potential makes use of for silicone elastomer compounds embody topical pharmaceutical formulations for prescription and over-the-counter merchandise that may enhance affected person compliance attributable to their distinctive sensory really feel, together with lotions that can be utilized for issues like atopic dermatitis, psoriasis, and scar and ache administration. and lotions and gels that supply a matte impact for treating zits. Silicone elastomer compounding methods are additionally recognized for his or her effectiveness in supporting drug launch or permeation in topical semi-solid formulations, offering choices for formulators.
The brand new DuPont Reside silicone resin compounds are:
Reside TE-9720 resin compound a mix of silicone resin dissolved in a 100 cSt The non-volatile service of Dimethicone (reference INCI names Dimethicone and Trimethylsiloxysilicate) varieties a movie and produces a long-lasting movie that resists water rinsing.
In growth: Reside TE-9721 resin compound A combination of silicone resin dissolved in Caprylyl Methicone unstable service (reference INCI names Caprylyl Methicone and Trimethylsiloxysilicate) varieties a movie and produces a long-lasting movie that resists water washing. As well as, it provides good compatibility with a number of formulation components.
Reside silicone resin blends may be simply included into many product varieties, together with lotions for pores and skin safety functions, easy-to-use and skin-protecting sprays, and gels into new product varieties for difficult pores and skin situations. Goal indications are pores and skin safety and protecting movies for stoma care; liquid dressings, pores and skin safety and scar administration for wound care; UV safety and sunscreens for skincare; and drug supply for zits, actinic keratosis, antifungals, and ache administration in skincare.
“DuPont serves a broad spectrum of shopper and medical topical healthcare functions, from over-the-counter to prescription,” Vigliotti stated. “Whether or not you are searching for technical experience, regulatory help or a variety of high quality topical excipients which are straightforward to deal with and affected person pleasant, we’re right here to help them.”
Reside topical silicone excipients embody silicone-based supplies that enable formulators to develop modern options for efficient supply of lively pharmaceutical components (APIs) in topical varieties equivalent to lotions, emulsions, gels, lotions, sprays, or suppositories. Excipients help distinctive and aesthetically interesting formulations, making ready-to-use pharmaceutical dosage varieties simpler to dispense and extra handy to make use of with out compromising drug supply effectivity, serving to to extend affected person compliance. Learn extra about Liveo at liveo.dupont.com.
Reside distributor accomplice Quimica San Diego will current DuPont’s new developments in low-cyclosiloxane silicone elastomer compounds and silicone resin compounds at ExpoFarma 2023 from 19 to 21. of April from 14:00 to 21:00 on the World Commerce Middle sales space 1216. Mexico Metropolis, Mexico.
About DuPont Reside Healthcare options
DuPont Reside is a globally acknowledged know-how chief providing a variety of improvements in medical units, biopharmaceutical processes and pharmaceutical options. Excessive-performance DuPont supplies assist create safer healthcare environments and defend the well being of sufferers and healthcare suppliers worldwide. We assist allow smarter healthcare and constructive affected person outcomes. Extra info may be discovered at liveo.dupont.com.
About DuPont Electronics & Industrial
DuPont Electronics & Industrial is a worldwide provider of latest applied sciences and efficiency supplies serving the semiconductor, circuit board, show, digital and flexo printing, healthcare, aerospace, industrial and transportation industries. Working from superior know-how facilities all over the world, groups of proficient researchers and utility consultants work intently with clients to ship options, merchandise and technical companies to allow next-generation applied sciences.
DuPont (NYSE: DD) is a worldwide innovation chief with technology-based supplies and options that assist rework industries and on a regular basis life. Our workers apply various science and experience to assist purchasers advance their greatest concepts and ship important improvements in key markets together with electronics, transportation, development, water, healthcare and employee security. Extra details about the corporate, its operations and options may be discovered at www.dupont.com. Buyers might entry info within the Investor Relations part of the web site at traders.dupont.com.
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